After much playing with different settings I've pretty much stabilized on this setup. Not that it's perfect, but it feels quite good over a broad range of operation. I have the Pod Mod, Screaming Demon twin pipes with "quiet" baffles (not very), and the airbox door removed.
I would like to pick up the mpg a bit more. I've tried leaner settings at cruise but it starts to feel flat. I average about 48 - 50 mpg right now. The speed I ride at on the freeway makes a noticeable difference in mpg. I seem to hit the reserve light at 140 miles like clockwork.
I use a accelerator pump setting of 20% trigger, 15 revs, and 20% fuel adjustment. This made a big difference up in the mid range in terms of response and really added that "brap factor" that big thumpers should have.
Here's my AFR target table. I run the Autotune 100% of the time. I found it works great for idle mixture control but you have to leave the AFR setting steady up a few thousand rpm or it will become a bit unstable as you come to stops. With these settings it's very stable. The 16 values from 3k rpm up to 6k are to quell the popping on the overrun.
Here's the fuel table. There are areas down around idle I manually edit back if I do an update because the updates foul up that region. I spent a fair amount time with low rpm range settings, especially starting as it's tricky to start when it's cold or near cold. I've found it's adding more fuel than needed which is why I have big negative numbers in the cranking rpm range. I've tried a lot of settings and this has produced the best results so far for starting. I believe the real problem is the idle control valve doesn't open up enough for good cold starting with the mods I have. When it was stock it wasn't much of an issue. To get better starting now you have to crack the throttle just the tiniest amount for about 1 or 2 revolutions to add a bit of air, then it will catch.